Sandbox Reserved 1771: Difference between revisions
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[[Image:B_Cell_Antigen-resized.png| 300 px|thumb | right| '''Figure 2.''' The Signal pathway for the response to an antigen by the B-cell receptor. Illustration reproduced courtesy of Cell Signaling Technology, Inc. ([https://www.cellsignal.com/ www.cellsignal.com]).]] | [[Image:B_Cell_Antigen-resized.png| 300 px|thumb | right| '''Figure 2.''' The Signal pathway for the response to an antigen by the B-cell receptor. Illustration reproduced courtesy of Cell Signaling Technology, Inc. ([https://www.cellsignal.com/ www.cellsignal.com]).]] | ||
The formation of B-cells occurs in the bone marrow from hematopoietic stem cells<ref name="Althwaiqeb">Althwaiqeb, S. ''Histology, B Cell Lymphocyte''; StatPearls Publishing, 2023. </ref>. Once formed, B-cell receptors are attached to B-cells through the aid of membrane-bound proteins in bone marrow cells. During this process, gene recombination occurs, which allows unique BCRs to become highly specific to different antigens. | The formation of B-cells occurs in the bone marrow from hematopoietic stem cells<ref name="Althwaiqeb">Althwaiqeb, S. ''Histology, B Cell Lymphocyte''; StatPearls Publishing, 2023. </ref>. Once formed, B-cell receptors are attached to B-cells through the aid of membrane-bound proteins in bone marrow cells. During this process, gene recombination occurs, which allows unique BCRs to become highly specific to different antigens. Once they are formed, B-cells diverge and become either memory cells or plasma cells. Memory cells still have BCRs and initiate a faster immune response, while plasma cells secrete antibodies in response to foreign antigens[https://en.wikipedia.org/wiki/B_cell]. | ||
===Disease=== | ===Disease=== | ||
