8deh: Difference between revisions

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'''Unreleased structure'''


The entry 8deh is ON HOLD  until Paper Publication
==Ankyrin domain of SKD3==
 
<StructureSection load='8deh' size='340' side='right'caption='[[8deh]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8deh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DEH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DEH FirstGlance]. <br>
Description:  
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8deh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8deh OCA], [https://pdbe.org/8deh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8deh RCSB], [https://www.ebi.ac.uk/pdbsum/8deh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8deh ProSAT]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
== Disease ==
[https://www.uniprot.org/uniprot/CLPB_HUMAN CLPB_HUMAN] 3-methylglutaconic aciduria type 7;Autosomal dominant severe congenital neutropenia. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/CLPB_HUMAN CLPB_HUMAN] May function as a regulatory ATPase and be related to secretion/protein trafficking process. Involved in mitochondrial-mediated antiviral innate immunity, activates RIG-I-mediated signal transduction and production of IFNB1 and pro-inflammatory cytokine IL6 (PubMed:31522117).<ref>PMID:31522117</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Lee S]]
[[Category: Tsai FTF]]