4y06: Difference between revisions

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<StructureSection load='4y06' size='340' side='right'caption='[[4y06]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
<StructureSection load='4y06' size='340' side='right'caption='[[4y06]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4y06]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700993 Atcc 700993]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y06 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y06 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4y06]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudoxanthomonas_mexicana Pseudoxanthomonas mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y06 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xzy|4xzy]], [[4y01|4y01]], [[4y02|4y02]], [[4y04|4y04]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y06 OCA], [https://pdbe.org/4y06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y06 RCSB], [https://www.ebi.ac.uk/pdbsum/4y06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y06 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dapb2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=128785 ATCC 700993])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y06 OCA], [http://pdbe.org/4y06 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y06 RCSB], [http://www.ebi.ac.uk/pdbsum/4y06 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y06 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DAPB2_PSEMX DAPB2_PSEMX] Exopeptidase that catalyzes the removal of dipeptide units (NH2-P2-P1-) from the free amino termini of oligopeptides and small proteins (PubMed:24598890, PubMed:8892831, PubMed:24827749). Peptide digestion is sequential and substrate recognition is non-specific, with the exception that Pro is not suitable as a P1 residue (PubMed:24827749). Removes many residues of bioactive oligopeptides such as angiotensin I and neuromedin N and cleaves also oxidized insulin B chain. Able to hydrolyze an X-Pro bond, an imido bond. No endopeptidase activity (PubMed:8892831). May play a physiological role in feeding (PubMed:24598890).<ref>PMID:24598890</ref> <ref>PMID:24827749</ref> <ref>PMID:8892831</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 700993]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Fujimoto, M]]
[[Category: Pseudoxanthomonas mexicana]]
[[Category: Iizuka, I]]
[[Category: Fujimoto M]]
[[Category: Nonaka, T]]
[[Category: Iizuka I]]
[[Category: Ogasawara, W]]
[[Category: Nonaka T]]
[[Category: Roppongi, S]]
[[Category: Ogasawara W]]
[[Category: Sakamoto, Y]]
[[Category: Roppongi S]]
[[Category: Tanaka, N]]
[[Category: Sakamoto Y]]
[[Category: Tateoka, C]]
[[Category: Tanaka N]]
[[Category: Hydrolase]]
[[Category: Tateoka C]]