4y4n: Difference between revisions
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<StructureSection load='4y4n' size='340' side='right'caption='[[4y4n]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='4y4n' size='340' side='right'caption='[[4y4n]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4y4n]] is a 8 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4y4n]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanotorris_igneus_Kol_5 Methanotorris igneus Kol 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y4N FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=48H:2-[(E)-[(4R)-5-[[[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHOXY-OXIDANYL-PHOSPHORYL]OXY-OXIDANYL-PHOSPHORYL]OXY-4-OXIDANYL-3-OXIDANYLIDENE-PENTAN-2-YLIDENE]AMINO]ETHANOIC+ACID'>48H</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=48H:2-[(E)-[(4R)-5-[[[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHOXY-OXIDANYL-PHOSPHORYL]OXY-OXIDANYL-PHOSPHORYL]OXY-4-OXIDANYL-3-OXIDANYLIDENE-PENTAN-2-YLIDENE]AMINO]ETHANOIC+ACID'>48H</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y4n OCA], [https://pdbe.org/4y4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y4n RCSB], [https://www.ebi.ac.uk/pdbsum/4y4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y4n ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/THI4_METIK THI4_METIK] Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.[HAMAP-Rule:MF_00304]<ref>PMID:26919468</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Methanotorris igneus Kol 5]] | ||
[[Category: Ealick SE]] | |||
[[Category: Ealick | [[Category: Zhang X]] | ||
[[Category: Zhang | |||