7zs7: Difference between revisions
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==Crystal structure of human cathepsin L with covalently bound calpain inhibitor VI== | |||
<StructureSection load='7zs7' size='340' side='right'caption='[[7zs7]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7zs7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZS7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZS7 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=JQO:(2S)-2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-[(2S)-4-methyl-1-oxidanyl-pentan-2-yl]butanamide'>JQO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zs7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zs7 OCA], [https://pdbe.org/7zs7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zs7 RCSB], [https://www.ebi.ac.uk/pdbsum/7zs7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zs7 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Chapman HN]] | |||
[[Category: Ewert W]] | |||
[[Category: Falke S]] | |||
[[Category: Guenther S]] | |||
[[Category: Hinrichs W]] | |||
[[Category: Karnicar K]] | |||
[[Category: Lieske J]] | |||
[[Category: Lindic N]] | |||
[[Category: Loboda J]] | |||
[[Category: Meents A]] | |||
[[Category: Reinke PYA]] | |||
[[Category: Sekirnik A]] | |||
[[Category: Turk D]] | |||
[[Category: Usenik A]] | |||
Revision as of 06:57, 18 May 2023
Crystal structure of human cathepsin L with covalently bound calpain inhibitor VI
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