4zm0: Difference between revisions

<StructureSection load='4zm0' size='340' side='right'caption='[[4zm0]], [[Resolution|resolution]] 3.17&Aring;' scene=''>

<table><tr><td colspan='2'>[[4zm0]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_P1 Escherichia virus P1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZM0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZM0 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=144:TRIS-HYDROXYMETHYL-METHYL-AMMONIUM'>144</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zm0 OCA], [https://pdbe.org/4zm0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zm0 RCSB], [https://www.ebi.ac.uk/pdbsum/4zm0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zm0 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/PHD_BPP1 PHD_BPP1] Antitoxin component of a toxin-antitoxin (TA) module. A labile antitoxin that binds to the doc toxin and neutralizes its toxic effect. Bacteriophage P1 lysogenizes bacteria as a low-copy number plasmid. Phd and doc proteins function in unison to stabilize plasmid number by inducing a lethal response to P1 plasmid prophage loss.<ref>PMID:9829946</ref> <ref>PMID:18398006</ref>  Binds to its own promoter repressing its expression; toxin doc acts as a corepressor or derepressor depending on the ratio, repressing or inducing expression.<ref>PMID:9829946</ref> <ref>PMID:18398006</ref>  

[[Category: Escherichia virus P1]]

[[Category: Large Structures]]

[[Category: Garcia-Pino A]]

[[Category: Loris R]]