4zqw: Difference between revisions

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<StructureSection load='4zqw' size='340' side='right'caption='[[4zqw]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4zqw' size='340' side='right'caption='[[4zqw]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4zqw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Eco5c Eco5c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZQW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZQW FirstGlance]. <br>
<table><tr><td colspan='2'>[[4zqw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7_str._EC869 Escherichia coli O157:H7 str. EC869]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZQW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZQW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ORN:L-ORNITHINE'>ORN</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ORN:L-ORNITHINE'>ORN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zqw OCA], [https://pdbe.org/4zqw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zqw RCSB], [https://www.ebi.ac.uk/pdbsum/4zqw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zqw ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cdiI4, cdiIo11, ECH7EC869_5884 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=478008 ECO5C])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zqw OCA], [http://pdbe.org/4zqw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zqw RCSB], [http://www.ebi.ac.uk/pdbsum/4zqw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zqw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CDII4_ECO5C CDII4_ECO5C]] Immunity protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion. Neutralizes the toxic activity of cognate toxin CdiA (C-terminal 289 residue CT fragment). Does not inhibit toxic activity of CdiA from other toxin-immunity modules or strains of E.coli.<ref>PMID:21829394</ref>  Expression of this locus confers protection against other bacteria carrying the locus.<ref>PMID:21829394</ref>
[https://www.uniprot.org/uniprot/CDII4_ECO5C CDII4_ECO5C] Immunity protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion. Neutralizes the toxic activity of cognate toxin CdiA (C-terminal 289 residue CT fragment). Does not inhibit toxic activity of CdiA from other toxin-immunity modules or strains of E.coli.<ref>PMID:21829394</ref>  Expression of this locus confers protection against other bacteria carrying the locus.<ref>PMID:21829394</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Eco5c]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli O157:H7 str. EC869]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Goulding, C W]]
[[Category: Goulding CW]]
[[Category: Morse, R P]]
[[Category: Morse RP]]
[[Category: Immunity]]
[[Category: Macrocycle]]
[[Category: Toxin]]
[[Category: Toxin-inhibitor complex]]
Retrieved from "https://proteopedia.org/4zqw"