4zv0: Difference between revisions

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<StructureSection load='4zv0' size='340' side='right'caption='[[4zv0]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='4zv0' size='340' side='right'caption='[[4zv0]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4zv0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZV0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZV0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4zv0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZV0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZV0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zv0 OCA], [https://pdbe.org/4zv0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zv0 RCSB], [https://www.ebi.ac.uk/pdbsum/4zv0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zv0 ProSAT]</span></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zuy|4zuy]], [[4zv4|4zv4]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA0093 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE]), PA0092 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zv0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zv0 OCA], [http://pdbe.org/4zv0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zv0 RCSB], [http://www.ebi.ac.uk/pdbsum/4zv0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zv0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TSE6_PSEAE TSE6_PSEAE] Type VI secretion exported toxin that acts as a glycohydrolase on bacterial target cells and degrades the essential dinucleotides NAD(+) and NADP(+), thereby inducing bacteriostasis. The activity resides in the C-terminal region that is initially neutralized by the cognate immunity protein Tsi6.<ref>PMID:26456113</ref> <ref>PMID:30177742</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pseae]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Mougous, J D]]
[[Category: Mougous JD]]
[[Category: Ralston, C]]
[[Category: Ralston C]]
[[Category: Sawai, S]]
[[Category: Sawai S]]
[[Category: Whitney, J C]]
[[Category: Whitney JC]]
[[Category: Protein binding]]
[[Category: T6ss effector-immunity pair]]
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