4zx4: Difference between revisions
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<StructureSection load='4zx4' size='340' side='right'caption='[[4zx4]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='4zx4' size='340' side='right'caption='[[4zx4]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4zx4]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4zx4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_FcB1/Columbia Plasmodium falciparum FcB1/Columbia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZX4 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4TL:N-[(1R)-2-(HYDROXYAMINO)-2-OXO-1-(3,4,5-TRIFLUOROBIPHENYL-4-YL)ETHYL]-2,2-DIMETHYLPROPANAMIDE'>4TL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4TL:N-[(1R)-2-(HYDROXYAMINO)-2-OXO-1-(3,4,5-TRIFLUOROBIPHENYL-4-YL)ETHYL]-2,2-DIMETHYLPROPANAMIDE'>4TL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zx4 OCA], [https://pdbe.org/4zx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zx4 RCSB], [https://www.ebi.ac.uk/pdbsum/4zx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zx4 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Plasmodium falciparum FcB1/Columbia]] | ||
[[Category: Drinkwater | [[Category: Drinkwater N]] | ||
[[Category: McGowan | [[Category: McGowan S]] | ||