5ab2: Difference between revisions

<table><tr><td colspan='2'>[[5ab2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AB2 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ab2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ab2 OCA], [https://pdbe.org/5ab2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ab2 RCSB], [https://www.ebi.ac.uk/pdbsum/5ab2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ab2 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ERAP2_HUMAN ERAP2_HUMAN] Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.<ref>PMID:12799365</ref> <ref>PMID:15908954</ref> <ref>PMID:16286653</ref>  

[[Category: Homo sapiens]]

[[Category: Giastas P]]

[[Category: Mavridis IM]]

[[Category: Mpakali A]]

[[Category: Saridakis E]]

[[Category: Stratikos E]]