5ad2: Difference between revisions
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<StructureSection load='5ad2' size='340' side='right'caption='[[5ad2]], [[Resolution|resolution]] 2.01Å' scene=''> | <StructureSection load='5ad2' size='340' side='right'caption='[[5ad2]], [[Resolution|resolution]] 2.01Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5ad2]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5ad2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AD2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AD2 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ETU:(3R)-4-(2-{4-[1-(3-CHLORO[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)-4-PIPERIDINYL]PHENOXY}ETHYL)-1,3-DIMETHYL-2-PIPERAZINONE'>ETU</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ETU:(3R)-4-(2-{4-[1-(3-CHLORO[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)-4-PIPERIDINYL]PHENOXY}ETHYL)-1,3-DIMETHYL-2-PIPERAZINONE'>ETU</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ad2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ad2 OCA], [https://pdbe.org/5ad2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ad2 RCSB], [https://www.ebi.ac.uk/pdbsum/5ad2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ad2 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bobby | [[Category: Bobby R]] | ||
[[Category: Boiko | [[Category: Boiko S]] | ||
[[Category: Bradbury | [[Category: Bradbury RH]] | ||
[[Category: Callis | [[Category: Callis R]] | ||
[[Category: Chen | [[Category: Chen H]] | ||
[[Category: Dale | [[Category: Dale I]] | ||
[[Category: Daniels | [[Category: Daniels D]] | ||
[[Category: Flavell | [[Category: Flavell L]] | ||
[[Category: Holdgate | [[Category: Holdgate G]] | ||
[[Category: Jowitt | [[Category: Jowitt TA]] | ||
[[Category: Kikhney | [[Category: Kikhney A]] | ||
[[Category: McAlister | [[Category: McAlister M]] | ||
[[Category: Ogg | [[Category: Ogg D]] | ||
[[Category: Patel | [[Category: Patel J]] | ||
[[Category: Petteruti | [[Category: Petteruti P]] | ||
[[Category: Rabow | [[Category: Rabow AA]] | ||
[[Category: Robb | [[Category: Robb GR]] | ||
[[Category: Robers | [[Category: Robers M]] | ||
[[Category: Stratton | [[Category: Stratton N]] | ||
[[Category: Svergun | [[Category: Svergun DI]] | ||
[[Category: Walker | [[Category: Walker G]] | ||
[[Category: Wang | [[Category: Wang W]] | ||
[[Category: Waring | [[Category: Waring MJ]] | ||
[[Category: Whittaker | [[Category: Whittaker D]] | ||