7xl5: Difference between revisions
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==Crystal structure of the H42T/A85G/I86A mutant of a nadp-dependent alcohol dehydrogenase== | |||
<StructureSection load='7xl5' size='340' side='right'caption='[[7xl5]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7xl5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoanaerobacter_brockii Thermoanaerobacter brockii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XL5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XL5 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xl5 OCA], [https://pdbe.org/7xl5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xl5 RCSB], [https://www.ebi.ac.uk/pdbsum/7xl5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xl5 ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/ADH_THEBR ADH_THEBR] Alcohol dehydrogenase with a preference for medium chain secondary alcohols, such as 2-butanol and isopropanol. Has very low activity with primary alcohols, such as ethanol. Under physiological conditions, the enzyme reduces aldehydes and 2-ketones to produce secondary alcohols. Is also active with acetaldehyde and propionaldehyde. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Thermoanaerobacter brockii]] | |||
[[Category: Han X]] | |||
[[Category: Jiang YY]] | |||
[[Category: Li X]] | |||
[[Category: Liu WD]] | |||
[[Category: Qu G]] | |||
[[Category: Sun ZT]] | |||
Revision as of 05:33, 31 May 2023
Crystal structure of the H42T/A85G/I86A mutant of a nadp-dependent alcohol dehydrogenase
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