8dve: Difference between revisions
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==RyR1 in presence of IpCa-T26E phosphomimetic and activating ligands== | |||
<StructureSection load='8dve' size='340' side='right'caption='[[8dve]], [[Resolution|resolution]] 3.84Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8dve]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DVE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DVE FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CFF:CAFFEINE'>CFF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dve OCA], [https://pdbe.org/8dve PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dve RCSB], [https://www.ebi.ac.uk/pdbsum/8dve PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dve ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FKB1B_HUMAN FKB1B_HUMAN] Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Oryctolagus cuniculus]] | |||
[[Category: Haji-Ghassemi O]] | |||
[[Category: Van Petegm F]] | |||