5ao5: Difference between revisions

<table><tr><td colspan='2'>[[5ao5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AO5 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ao5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ao5 OCA], [https://pdbe.org/5ao5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ao5 RCSB], [https://www.ebi.ac.uk/pdbsum/5ao5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ao5 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/MRC2_HUMAN MRC2_HUMAN] May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).<ref>PMID:10683150</ref> <ref>PMID:12972549</ref>  

[[Category: Briggs DC]]

[[Category: Carafoli F]]

[[Category: Hohenester E]]

[[Category: Loncar T]]

[[Category: Paracuellos P]]