5ayg: Difference between revisions

<table><tr><td colspan='2'>[[5ayg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AYG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AYG FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4LQ:3-[5-(2-CYCLOHEXYLETHYL)-4-ETHYL-1,2,4-TRIAZOL-3-YL]-N-NAPHTHALEN-1-YL-PROPANAMIDE'>4LQ</scene></td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RORC, NR1F3, RORG, RZRG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ayg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ayg OCA], [http://pdbe.org/5ayg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ayg RCSB], [http://www.ebi.ac.uk/pdbsum/5ayg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ayg ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/RORG_HUMAN RORG_HUMAN]] Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment. Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T-helper cells into Th17 cells. Regulate the expression of several components of the circadian clock.  

[[Category: Human]]

[[Category: Adachi, T]]

[[Category: Doi, S]]

[[Category: Hirata, K]]

[[Category: Kamada, M]]

[[Category: Kikuwaka, M]]

[[Category: Murase, K]]

[[Category: Noguchi, M]]

[[Category: Nomura, A]]

[[Category: Nuclear receptor]]