5bqi: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
Line 3: Line 3:
<StructureSection load='5bqi' size='340' side='right'caption='[[5bqi]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
<StructureSection load='5bqi' size='340' side='right'caption='[[5bqi]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5bqi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BQI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BQI FirstGlance]. <br>
<table><tr><td colspan='2'>[[5bqi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BQI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BQI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1KA:(2-HYDROXYETHOXY)ACETALDEHYDE'>1KA</scene>, <scene name='pdbligand=4UL:2-(DIFLUOROMETHYL)-5-{[(2-METHYLPROPANOYL)AMINO]METHYL}-N-{5-METHYL-4-[4-(TRIFLUOROMETHYL)PHENYL]-1H-IMIDAZOL-2-YL}PYRIDINE-3-CARBOXAMIDE'>4UL</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1KA:(2-HYDROXYETHOXY)ACETALDEHYDE'>1KA</scene>, <scene name='pdbligand=4UL:2-(DIFLUOROMETHYL)-5-{[(2-METHYLPROPANOYL)AMINO]METHYL}-N-{5-METHYL-4-[4-(TRIFLUOROMETHYL)PHENYL]-1H-IMIDAZOL-2-YL}PYRIDINE-3-CARBOXAMIDE'>4UL</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTGES, MGST1L1, MPGES1, PGES, PIG12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bqi OCA], [https://pdbe.org/5bqi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bqi RCSB], [https://www.ebi.ac.uk/pdbsum/5bqi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bqi ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bqi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bqi OCA], [http://pdbe.org/5bqi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bqi RCSB], [http://www.ebi.ac.uk/pdbsum/5bqi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bqi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PTGES_HUMAN PTGES_HUMAN]] Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).<ref>PMID:18682561</ref>
[https://www.uniprot.org/uniprot/PTGES_HUMAN PTGES_HUMAN] Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).<ref>PMID:18682561</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 27: Line 25:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Prostaglandin-E synthase]]
[[Category: Antonysamy S]]
[[Category: Antonysamy, S]]
[[Category: Fisher MJ]]
[[Category: Fisher, M J]]
[[Category: Kuklish SL]]
[[Category: Kuklish, S L]]
[[Category: Luz JG]]
[[Category: Luz, J G]]
[[Category: Schiffler MA]]
[[Category: Schiffler, M A]]
[[Category: Enzyme]]
[[Category: Integral membrane protein]]
[[Category: Isomerase-isomerase inhibitor complex]]
[[Category: Mpges-1]]
[[Category: Targetname]]
Retrieved from "https://proteopedia.org/5bqi"