5bt1: Difference between revisions

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<StructureSection load='5bt1' size='340' side='right'caption='[[5bt1]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
<StructureSection load='5bt1' size='340' side='right'caption='[[5bt1]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5bt1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BT1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BT1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5bt1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BT1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BT1 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nq0|4nq0]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bt1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bt1 OCA], [https://pdbe.org/5bt1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bt1 RCSB], [https://www.ebi.ac.uk/pdbsum/5bt1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bt1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bt1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bt1 OCA], [http://pdbe.org/5bt1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bt1 RCSB], [http://www.ebi.ac.uk/pdbsum/5bt1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bt1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HIF1_YEAST HIF1_YEAST]] Histone H3 and H4 specific chaperone component of the nuclear histone acetyltransferase B (HAT-B) complex. Involved in chromatin assembly and telomere silencing.<ref>PMID:14761951</ref> <ref>PMID:15099519</ref> [[http://www.uniprot.org/uniprot/H2B1_YEAST H2B1_YEAST]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<ref>PMID:11973294</ref> <ref>PMID:12152067</ref> <ref>PMID:14752010</ref> <ref>PMID:15280549</ref> <ref>PMID:15652479</ref> <ref>PMID:15970663</ref> <ref>PMID:15632126</ref> <ref>PMID:15632065</ref> <ref>PMID:16598039</ref>  [[http://www.uniprot.org/uniprot/H2A1_YEAST H2A1_YEAST]] Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<ref>PMID:11140636</ref> <ref>PMID:15458641</ref> <ref>PMID:15610741</ref> <ref>PMID:16299494</ref> 
[https://www.uniprot.org/uniprot/HIF1_YEAST HIF1_YEAST] Histone H3 and H4 specific chaperone component of the nuclear histone acetyltransferase B (HAT-B) complex. Involved in chromatin assembly and telomere silencing.<ref>PMID:14761951</ref> <ref>PMID:15099519</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Gao, Y]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Liu, H]]
[[Category: Gao Y]]
[[Category: Niu, L]]
[[Category: Liu H]]
[[Category: Teng, M]]
[[Category: Niu L]]
[[Category: Zhang, M]]
[[Category: Teng M]]
[[Category: Assembly]]
[[Category: Zhang M]]
[[Category: Chaperone]]
[[Category: Histone chaperone complex]]
[[Category: Nasp homolog]]
[[Category: Tpr]]

Revision as of 06:07, 7 June 2023

histone chaperone Hif1 playing with histone H2A-H2B dimer

5bt1, resolution 2.62Å

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