5bxb: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:


==Crystal structure of pentameric KCTD1 BTB domain form 1==
==Crystal structure of pentameric KCTD1 BTB domain form 1==
<StructureSection load='5bxb' size='340' side='right' caption='[[5bxb]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
<StructureSection load='5bxb' size='340' side='right'caption='[[5bxb]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5bxb]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BXB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BXB FirstGlance]. <br>
<table><tr><td colspan='2'>[[5bxb]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BXB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BXB FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5bxd|5bxd]], [[5bxh|5bxh]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bxb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bxb OCA], [https://pdbe.org/5bxb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bxb RCSB], [https://www.ebi.ac.uk/pdbsum/5bxb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bxb ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KCTD1, C18orf5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bxb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bxb OCA], [http://pdbe.org/5bxb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bxb RCSB], [http://www.ebi.ac.uk/pdbsum/5bxb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bxb ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/KCTD1_HUMAN KCTD1_HUMAN]] Scalp-ear-nipple syndrome. The disease is caused by mutations affecting the gene represented in this entry.  
[https://www.uniprot.org/uniprot/KCTD1_HUMAN KCTD1_HUMAN] Scalp-ear-nipple syndrome. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KCTD1_HUMAN KCTD1_HUMAN]] May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.<ref>PMID:18358072</ref> <ref>PMID:19115315</ref>
[https://www.uniprot.org/uniprot/KCTD1_HUMAN KCTD1_HUMAN] May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.<ref>PMID:18358072</ref> <ref>PMID:19115315</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 25: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Chu, A]]
[[Category: Large Structures]]
[[Category: Ji, A X]]
[[Category: Chu A]]
[[Category: Prive, G G]]
[[Category: Ji AX]]
[[Category: Protein binding]]
[[Category: Prive GG]]