5bym: Difference between revisions

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==Crystal structure of the RNA-binding domain of yeast Puf5p bound to SMX2 RNA==
==Crystal structure of the RNA-binding domain of yeast Puf5p bound to SMX2 RNA==
<StructureSection load='5bym' size='340' side='right' caption='[[5bym]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
<StructureSection load='5bym' size='340' side='right'caption='[[5bym]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5bym]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BYM FirstGlance]. <br>
<table><tr><td colspan='2'>[[5bym]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BYM FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5bz1|5bz1]], [[5bz5|5bz5]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bym OCA], [https://pdbe.org/5bym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bym RCSB], [https://www.ebi.ac.uk/pdbsum/5bym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bym ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MPT5, HTR1, PUF5, YGL178W, BIC834 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bym OCA], [http://pdbe.org/5bym PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bym RCSB], [http://www.ebi.ac.uk/pdbsum/5bym PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bym ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MPT5_YEAST MPT5_YEAST]] RNA-binding protein involved in post-transcriptional regulation. Negatively regulates expression of HO by binding to the 3'-UTR of HO mRNA. Predominantly binds to mRNAs encoding chromatin modifiers and spindle pole body components. Recognizes and binds to 5'-TGTAA[CT]A[AT]TA-3' in the 3'-UTR of target mRNAs. Multicopy suppressor of POP2 mutation. Required for high temperature growth.<ref>PMID:11157761</ref>
[https://www.uniprot.org/uniprot/MPT5_YEAST MPT5_YEAST] RNA-binding protein involved in post-transcriptional regulation. Negatively regulates expression of HO by binding to the 3'-UTR of HO mRNA. Predominantly binds to mRNAs encoding chromatin modifiers and spindle pole body components. Recognizes and binds to 5'-TGTAA[CT]A[AT]TA-3' in the 3'-UTR of target mRNAs. Multicopy suppressor of POP2 mutation. Required for high temperature growth.<ref>PMID:11157761</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Hall, T M.T]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Qiu, C]]
[[Category: Synthetic construct]]
[[Category: Puf rna-binding domain]]
[[Category: Hall TMT]]
[[Category: Rna binding protein-rna complex]]
[[Category: Qiu C]]
Retrieved from "https://proteopedia.org/5bym"