5c3f: Difference between revisions
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<StructureSection load='5c3f' size='340' side='right'caption='[[5c3f]], [[Resolution|resolution]] 1.43Å' scene=''> | <StructureSection load='5c3f' size='340' side='right'caption='[[5c3f]], [[Resolution|resolution]] 1.43Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5c3f]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C3F OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5c3f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C3F FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand= | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NLE:NORLEUCINE'>NLE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c3f OCA], [https://pdbe.org/5c3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c3f RCSB], [https://www.ebi.ac.uk/pdbsum/5c3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c3f ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MCL1_HUMAN MCL1_HUMAN] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.<ref>PMID:10766760</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Edwards | [[Category: Edwards TA]] | ||
[[Category: Miles | [[Category: Miles JA]] | ||
[[Category: Pask | [[Category: Pask CM]] | ||
[[Category: Rodriguez-Marin | [[Category: Rodriguez-Marin S]] | ||
[[Category: Rowell | [[Category: Rowell P]] | ||
[[Category: Warriner | [[Category: Warriner SL]] | ||
[[Category: Wilson | [[Category: Wilson AJ]] | ||
[[Category: Yeo | [[Category: Yeo DJ]] | ||