5c9n: Difference between revisions

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==Crystal structure of GEMC1 coiled-coil domain==
==Crystal structure of GEMC1 coiled-coil domain==
<StructureSection load='5c9n' size='340' side='right' caption='[[5c9n]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='5c9n' size='340' side='right'caption='[[5c9n]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5c9n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C9N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C9N FirstGlance]. <br>
<table><tr><td colspan='2'>[[5c9n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C9N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C9N FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GMNC, GEMC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c9n OCA], [https://pdbe.org/5c9n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c9n RCSB], [https://www.ebi.ac.uk/pdbsum/5c9n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c9n ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c9n OCA], [http://pdbe.org/5c9n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c9n RCSB], [http://www.ebi.ac.uk/pdbsum/5c9n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c9n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GEMC1_HUMAN GEMC1_HUMAN]] Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2-dependent recruitment of CDC45L onto replication origins (By similarity).  
[https://www.uniprot.org/uniprot/GEMC1_HUMAN GEMC1_HUMAN] Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2-dependent recruitment of CDC45L onto replication origins (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Caillat, C]]
[[Category: Large Structures]]
[[Category: Perrakis, A]]
[[Category: Caillat C]]
[[Category: Cell cycle]]
[[Category: Perrakis A]]
[[Category: Geminin idas coiled coil dna replication license]]
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