7t5q: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "7t5q" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
==Cryo-EM structure of an Arp2/3 complex mini-branch capped by capping protein (CapZ)== | |||
<StructureSection load='7t5q' size='340' side='right'caption='[[7t5q]], [[Resolution|resolution]] 3.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7t5q]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7T5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7T5Q FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t5q OCA], [https://pdbe.org/7t5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t5q RCSB], [https://www.ebi.ac.uk/pdbsum/7t5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t5q ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ARC1A_BOVIN ARC1A_BOVIN] Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (By similarity). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity).[UniProtKB:Q8AVT9][UniProtKB:Q92747] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bos taurus]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Oryctolagus cuniculus]] | |||
[[Category: Boczkowska M]] | |||
[[Category: Dominguez R]] | |||
[[Category: Rebowski G]] | |||
[[Category: Van Eeuwen T]] | |||