2c06: Difference between revisions

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==NMR-based model of the complex of the toxin Kid and a 5-nucleotide substrate RNA fragment (AUACA)==
==NMR-based model of the complex of the toxin Kid and a 5-nucleotide substrate RNA fragment (AUACA)==
<StructureSection load='2c06' size='340' side='right'caption='[[2c06]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2c06' size='340' side='right'caption='[[2c06]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2c06]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C06 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2c06]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C06 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1m1f|1m1f]]</div></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c06 OCA], [https://pdbe.org/2c06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c06 RCSB], [https://www.ebi.ac.uk/pdbsum/2c06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c06 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c06 OCA], [https://pdbe.org/2c06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c06 RCSB], [https://www.ebi.ac.uk/pdbsum/2c06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c06 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PEMK_ECOLX PEMK_ECOLX]] Toxic component of a type II toxin-antitoxin (TA) module. Probably functions as an endoribonuclease. Responsible for the stable maintenance of the plasmid during cell division by postsegregational killing of plasmid-less daughter cells. Neutralized by coexpression with cognate antitoxin PemI. Both PemI and PemK proteins bind to the promoter region of the pem operon to autoregulate their synthesis.<ref>PMID:2832364</ref> <ref>PMID:8455570</ref>
[https://www.uniprot.org/uniprot/PEMK_ECOLX PEMK_ECOLX] Toxic component of a type II toxin-antitoxin (TA) module. Probably functions as an endoribonuclease. Responsible for the stable maintenance of the plasmid during cell division by postsegregational killing of plasmid-less daughter cells. Neutralized by coexpression with cognate antitoxin PemI. Both PemI and PemK proteins bind to the promoter region of the pem operon to autoregulate their synthesis.<ref>PMID:2832364</ref> <ref>PMID:8455570</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Boelens, R]]
[[Category: Boelens R]]
[[Category: Bonvin, A M.J J]]
[[Category: Bonvin AMJJ]]
[[Category: Diaz-Orejas, R]]
[[Category: Diaz-Orejas R]]
[[Category: Heuvel, R H.H Van Den]]
[[Category: Kamphuis MB]]
[[Category: Kamphuis, M B]]
[[Category: Lemonnier M]]
[[Category: Lemonnier, M]]
[[Category: Monti MC]]
[[Category: Monti, M C]]
[[Category: Munoz-Gomez A]]
[[Category: Munoz-Gomez, A]]
[[Category: Van Den Heuvel RHH]]
[[Category: Dna replication]]
[[Category: Docking]]
[[Category: Mazf]]
[[Category: Plasmid maintenance]]
[[Category: Post segregational killing]]
[[Category: Protein-rna complex]]
[[Category: Ribonuclease]]
[[Category: Rna cleavage]]
[[Category: Rnase]]
[[Category: Toxin]]
[[Category: Toxin-antitoxin]]
Retrieved from "https://proteopedia.org/2c06"