2i59: Difference between revisions

<StructureSection load='2i59' size='340' side='right'caption='[[2i59]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>

<table><tr><td colspan='2'>[[2i59]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I59 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I59 FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RGS10 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i59 OCA], [https://pdbe.org/2i59 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i59 RCSB], [https://www.ebi.ac.uk/pdbsum/2i59 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i59 ProSAT]</span></td></tr>

[[https://www.uniprot.org/uniprot/RGS10_HUMAN RGS10_HUMAN]] Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)-alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity on G(z)-alpha is inhibited by palmitoylation of the G-protein.  

[[Category: Human]]

[[Category: Arrowsmith, C]]

[[Category: Ball, L J]]

[[Category: Diehl, A]]

[[Category: Doyle, D A]]

[[Category: Edwards, A]]

[[Category: Elkins, J]]

[[Category: Fedorov, O]]

[[Category: Higman, V A]]

[[Category: Leidert, M]]

[[Category: Lemak, A]]

[[Category: Oschkinat, H]]

[[Category: Structural genomic]]

[[Category: Schmieder, P]]

[[Category: Soundarajan, M]]

[[Category: Sundstrom, M]]

[[Category: Weigelt, J]]

[[Category: Signaling protein]]