2jm2: Difference between revisions
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==Structure of the N-terminal subdomain of insulin-like growth factor (IGF) binding protein-6 and its interactions with IGFs== | ==Structure of the N-terminal subdomain of insulin-like growth factor (IGF) binding protein-6 and its interactions with IGFs== | ||
<StructureSection load='2jm2' size='340' side='right'caption='[[2jm2 | <StructureSection load='2jm2' size='340' side='right'caption='[[2jm2]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jm2]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JM2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JM2 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2jm2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JM2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JM2 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jm2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jm2 OCA], [https://pdbe.org/2jm2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jm2 RCSB], [https://www.ebi.ac.uk/pdbsum/2jm2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jm2 ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jm2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jm2 OCA], [https://pdbe.org/2jm2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jm2 RCSB], [https://www.ebi.ac.uk/pdbsum/2jm2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jm2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/IBP6_HUMAN IBP6_HUMAN] IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Alewood | [[Category: Alewood PF]] | ||
[[Category: Bach | [[Category: Bach LA]] | ||
[[Category: Bansal | [[Category: Bansal PS]] | ||
[[Category: Chandrashekaran | [[Category: Chandrashekaran IR]] | ||
[[Category: Forbes | [[Category: Forbes BE]] | ||
[[Category: Norton | [[Category: Norton RS]] | ||
[[Category: Wallace | [[Category: Wallace JC]] | ||
[[Category: Wang | [[Category: Wang CC]] | ||
[[Category: Yao | [[Category: Yao S]] | ||
