2jpe: Difference between revisions
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==FHA domain of NIPP1== | ==FHA domain of NIPP1== | ||
<StructureSection load='2jpe' size='340' side='right'caption='[[2jpe | <StructureSection load='2jpe' size='340' side='right'caption='[[2jpe]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jpe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2jpe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JPE FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jpe OCA], [https://pdbe.org/2jpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jpe RCSB], [https://www.ebi.ac.uk/pdbsum/2jpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jpe ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jpe OCA], [https://pdbe.org/2jpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jpe RCSB], [https://www.ebi.ac.uk/pdbsum/2jpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jpe ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/PP1R8_MOUSE PP1R8_MOUSE] Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Essential for cell proliferation and early embryonic development.<ref>PMID:15501817</ref> <ref>PMID:15199142</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Fujioka | [[Category: Fujioka Y]] | ||
[[Category: Inagaki | [[Category: Inagaki F]] | ||
[[Category: Kikuchi | [[Category: Kikuchi K]] | ||
[[Category: Kumeta | [[Category: Kumeta H]] | ||
[[Category: Ogura | [[Category: Ogura K]] | ||
[[Category: Tanuma | [[Category: Tanuma N]] | ||
