2kwh: Difference between revisions

<StructureSection load='2kwh' size='340' side='right'caption='[[2kwh]]' scene=''>

<table><tr><td colspan='2'>[[2kwh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KWH FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kwh OCA], [https://pdbe.org/2kwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kwh RCSB], [https://www.ebi.ac.uk/pdbsum/2kwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kwh ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/RBP1_HUMAN RBP1_HUMAN] Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.<ref>PMID:7673236</ref> <ref>PMID:12775724</ref> <ref>PMID:11437348</ref>  

[[Category: Homo sapiens]]

[[Category: Camonis J]]

[[Category: Campbell LJ]]

[[Category: Fenwick RB]]

[[Category: Mott HR]]

[[Category: Nietlispach D]]

[[Category: Owen D]]

[[Category: Prasannan S]]

[[Category: Rajasekar K]]