2l75: Difference between revisions

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==Solution structure of CHD4-PHD2 in complex with H3K9me3==
==Solution structure of CHD4-PHD2 in complex with H3K9me3==
<StructureSection load='2l75' size='340' side='right'caption='[[2l75]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2l75' size='340' side='right'caption='[[2l75]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2l75]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L75 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L75 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2l75]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L75 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L75 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHD4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l75 OCA], [https://pdbe.org/2l75 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l75 RCSB], [https://www.ebi.ac.uk/pdbsum/2l75 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l75 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l75 OCA], [https://pdbe.org/2l75 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l75 RCSB], [https://www.ebi.ac.uk/pdbsum/2l75 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l75 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/CHD4_HUMAN CHD4_HUMAN]] Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.<ref>PMID:9804427</ref> <ref>PMID:17626165</ref>
[https://www.uniprot.org/uniprot/CHD4_HUMAN CHD4_HUMAN] Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.<ref>PMID:9804427</ref> <ref>PMID:17626165</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Kwan, A H]]
[[Category: Kwan AH]]
[[Category: Mackay, J P]]
[[Category: Mackay JP]]
[[Category: Mansfield, R E]]
[[Category: Mansfield RE]]
[[Category: Chd4]]
[[Category: H3k9me3]]
[[Category: Mi2b]]
[[Category: Phd2]]
[[Category: Transcription-nuclear protein complex]]