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==20 lowest energy ensemble of dermcidin (DCD1L) NMR structure==
==20 lowest energy ensemble of dermcidin (DCD1L) NMR structure==
<StructureSection load='2ndk' size='340' side='right'caption='[[2ndk]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2ndk' size='340' side='right'caption='[[2ndk]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ndk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NDK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NDK FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ndk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NDK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NDK FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DCD, AIDD, DSEP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ndk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ndk OCA], [https://pdbe.org/2ndk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ndk RCSB], [https://www.ebi.ac.uk/pdbsum/2ndk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ndk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ndk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ndk OCA], [https://pdbe.org/2ndk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ndk RCSB], [https://www.ebi.ac.uk/pdbsum/2ndk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ndk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/DCD_HUMAN DCD_HUMAN]] DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity.<ref>PMID:17448443</ref>  Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG.<ref>PMID:17448443</ref>
[https://www.uniprot.org/uniprot/DCD_HUMAN DCD_HUMAN] DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity.<ref>PMID:17448443</ref>  Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG.<ref>PMID:17448443</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Mok, Y K]]
[[Category: Mok YK]]
[[Category: Tan, K W]]
[[Category: Tan KW]]
[[Category: Antimicrobial]]
[[Category: Dcd1l]]
[[Category: Dermcidin]]
[[Category: Hydrolase]]
Retrieved from "https://proteopedia.org/2ndk"