6h3e: Difference between revisions
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==Receptor-bound Ghrelin conformation== | ==Receptor-bound Ghrelin conformation== | ||
<StructureSection load='6h3e' size='340' side='right'caption='[[6h3e | <StructureSection load='6h3e' size='340' side='right'caption='[[6h3e]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6h3e]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H3E OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[6h3e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6H3E FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FKZ:octan-1-amine'>FKZ</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FKZ:octan-1-amine'>FKZ</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6h3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h3e OCA], [https://pdbe.org/6h3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6h3e RCSB], [https://www.ebi.ac.uk/pdbsum/6h3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6h3e ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GHRL_HUMAN GHRL_HUMAN] Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Baneres | [[Category: Baneres JL]] | ||
[[Category: Czaplicki | [[Category: Czaplicki G]] | ||
[[Category: Damian | [[Category: Damian M]] | ||
[[Category: Demange | [[Category: Demange P]] | ||
[[Category: Fehrentz | [[Category: Fehrentz JA]] | ||
[[Category: Ferre | [[Category: Ferre G]] | ||
[[Category: Kadmi | [[Category: M'Kadmi C]] | ||
[[Category: Marie | [[Category: Marie J]] | ||
[[Category: Milon | [[Category: Milon A]] | ||
[[Category: Saurel | [[Category: Saurel O]] | ||