6i3r: Difference between revisions

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==Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1/2 of Drosophila helicase MLE==
==Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1/2 of Drosophila helicase MLE==
<StructureSection load='6i3r' size='340' side='right'caption='[[6i3r]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='6i3r' size='340' side='right'caption='[[6i3r]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6i3r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I3R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I3R FirstGlance]. <br>
<table><tr><td colspan='2'>[[6i3r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6I3R FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mle, nap, CG11680 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6i3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i3r OCA], [https://pdbe.org/6i3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6i3r RCSB], [https://www.ebi.ac.uk/pdbsum/6i3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6i3r ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i3r OCA], [http://pdbe.org/6i3r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i3r RCSB], [http://www.ebi.ac.uk/pdbsum/6i3r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i3r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MLE_DROME MLE_DROME]] Required in males for dosage compensation of X chromosome linked genes. Mle, msl-1 and msl-3 are colocalized on X chromosome. Each of the msl proteins requires all the other msls for wild-type X-chromosome binding. Probably unwinds double-stranded DNA and RNA in a 3' to 5' direction.<ref>PMID:1653648</ref>
[https://www.uniprot.org/uniprot/MLE_DROME MLE_DROME] Required in males for dosage compensation of X chromosome linked genes. Mle, msl-1 and msl-3 are colocalized on X chromosome. Each of the msl proteins requires all the other msls for wild-type X-chromosome binding. Probably unwinds double-stranded DNA and RNA in a 3' to 5' direction.<ref>PMID:1653648</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Drome]]
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: RNA helicase]]
[[Category: Buelow Sv]]
[[Category: Buelow, S v]]
[[Category: Hennig J]]
[[Category: Hennig, J]]
[[Category: Jagtap PKA]]
[[Category: Jagtap, P K.A]]
[[Category: Masiewicz P]]
[[Category: Masiewicz, P]]
[[Category: Simon B]]
[[Category: Simon, B]]
[[Category: Dsrbd]]
[[Category: Helicase]]
[[Category: Rna binding protein]]
Retrieved from "https://proteopedia.org/6i3r"