6z0h: Difference between revisions

<StructureSection load='6z0h' size='340' side='right'caption='[[6z0h]]' scene=''>

<table><tr><td colspan='2'>[[6z0h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Z0H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Z0H FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6z0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6z0h OCA], [https://pdbe.org/6z0h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6z0h RCSB], [https://www.ebi.ac.uk/pdbsum/6z0h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6z0h ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] Progressive non-fluent aphasia;Amyotrophic lateral sclerosis;Nasu-Hakola disease;Semantic dementia;Behavioral variant of frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.

[https://www.uniprot.org/uniprot/TREM2_HUMAN TREM2_HUMAN] May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.<ref>PMID:10799849</ref>  

[[Category: Homo sapiens]]

[[Category: Brunner B]]

[[Category: Haass C]]

[[Category: Hagn F]]

[[Category: Schlepkow K]]

[[Category: Steiner A]]

[[Category: Steiner H]]