5dg3: Difference between revisions

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==Structure of Pseudomonas aeruginosa LpxA in complex with UDP-3-O-(R-3-hydroxydecanoyl)-GlcNAc==
==Structure of Pseudomonas aeruginosa LpxA in complex with UDP-3-O-(R-3-hydroxydecanoyl)-GlcNAc==
<StructureSection load='5dg3' size='340' side='right' caption='[[5dg3]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='5dg3' size='340' side='right'caption='[[5dg3]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5dg3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Psea7 Psea7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DG3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DG3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5dg3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PA7 Pseudomonas aeruginosa PA7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DG3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DG3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=U21:URIDINE-5-DIPHOSPHATE-3-O-(R-3-HYDROXYDECANOYL)-N-ACETYL-D-GLUCOSAMINE'>U21</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=U21:URIDINE-5-DIPHOSPHATE-3-O-(R-3-HYDROXYDECANOYL)-N-ACETYL-D-GLUCOSAMINE'>U21</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dep|5dep]], [[5dem|5dem]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dg3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dg3 OCA], [https://pdbe.org/5dg3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dg3 RCSB], [https://www.ebi.ac.uk/pdbsum/5dg3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dg3 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lpxA, PSPA7_1495 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=381754 PSEA7])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine_O-acyltransferase Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.129 2.3.1.129] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dg3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dg3 OCA], [http://pdbe.org/5dg3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dg3 RCSB], [http://www.ebi.ac.uk/pdbsum/5dg3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dg3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LPXA_PSEA7 LPXA_PSEA7]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.  
[https://www.uniprot.org/uniprot/LPXA_PSEA7 LPXA_PSEA7] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5dg3" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5dg3" style="background-color:#fffaf0;"></div>
==See Also==
*[[UDP-N-acetylglucosamine acyltransferase|UDP-N-acetylglucosamine acyltransferase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Psea7]]
[[Category: Large Structures]]
[[Category: Chen, Y]]
[[Category: Pseudomonas aeruginosa PA7]]
[[Category: Smith, E W]]
[[Category: Chen Y]]
[[Category: Acyltransferase]]
[[Category: Smith EW]]
[[Category: Catalytic domain]]
[[Category: Fatty acid]]
[[Category: Hydrocarbon ruler]]
[[Category: Lipid some]]
[[Category: Substrate specificity]]
[[Category: Transferase]]
[[Category: Udp-glcnac]]
[[Category: Uridine diphosphate n-acetylglucosamine]]