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==STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS==
==STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS==
<StructureSection load='1lcd' size='340' side='right'caption='[[1lcd]], [[NMR_Ensembles_of_Models | 3 NMR models]]' scene=''>
<StructureSection load='1lcd' size='340' side='right'caption='[[1lcd]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1lcd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LCD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LCD FirstGlance]. <br>
<table><tr><td colspan='2'>[[1lcd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LCD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LCD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1lcc|1lcc]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lcd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lcd OCA], [https://pdbe.org/1lcd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lcd RCSB], [https://www.ebi.ac.uk/pdbsum/1lcd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lcd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lcd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lcd OCA], [https://pdbe.org/1lcd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lcd RCSB], [https://www.ebi.ac.uk/pdbsum/1lcd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lcd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI]] Repressor of the lactose operon. Binds allolactose as an inducer.  
[https://www.uniprot.org/uniprot/LACI_ECOLI LACI_ECOLI] Repressor of the lactose operon. Binds allolactose as an inducer.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Boelens, R]]
[[Category: Boelens R]]
[[Category: Boom, J H.Van]]
[[Category: Chuprina VP]]
[[Category: Chuprina, V P]]
[[Category: Kaptein R]]
[[Category: Kaptein, R]]
[[Category: Lamerichs RMJN]]
[[Category: Lamerichs, R M.J N]]
[[Category: Rullmann JAC]]
[[Category: Rullmann, J A.C]]
[[Category: Van Boom JH]]
[[Category: Gene regulation-dna complex]]
[[Category: Gene regulation/dna]]
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