5dgm: Difference between revisions

<table><tr><td colspan='2'>[[5dgm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DGM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5DGM FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=59Z:{2-[(PHOSPHONOMETHYL)CARBAMOYL]-1H-BENZO[G]INDOL-1-YL}ACETIC+ACID'>59Z</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FDPS, FPS, KIAA1293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5dgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dgm OCA], [http://pdbe.org/5dgm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dgm RCSB], [http://www.ebi.ac.uk/pdbsum/5dgm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dgm ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN]] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.  

[[Category: Human]]

[[Category: Bourgier, E]]

[[Category: Lehmann, S]]

[[Category: Rondeau, J M]]

[[Category: Transferase]]