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==Crystal structure of Phosphoribosyl isomerase A from Streptomyces coelicolor==
==Crystal structure of Phosphoribosyl isomerase A from Streptomyces coelicolor==
<StructureSection load='5dn1' size='340' side='right' caption='[[5dn1]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='5dn1' size='340' side='right'caption='[[5dn1]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5dn1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strco Strco]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DN1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DN1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5dn1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor_A3(2) Streptomyces coelicolor A3(2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DN1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMZ:AMINOIMIDAZOLE+4-CARBOXAMIDE+RIBONUCLEOTIDE'>AMZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.953&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">priA, hisA, SCO2050, SC4G6.19c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=100226 STRCO])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMZ:AMINOIMIDAZOLE+4-CARBOXAMIDE+RIBONUCLEOTIDE'>AMZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dn1 OCA], [http://pdbe.org/5dn1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dn1 RCSB], [http://www.ebi.ac.uk/pdbsum/5dn1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dn1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dn1 OCA], [https://pdbe.org/5dn1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dn1 RCSB], [https://www.ebi.ac.uk/pdbsum/5dn1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dn1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HIS4_STRCO HIS4_STRCO]] Catalyzes the isomerization of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR in the biosynthesis pathway for histidine and the isomerization of the aminoaldose PRA to the aminoketose CdRP in the biosynthsis pathway for tryptophan.[HAMAP-Rule:MF_01014]  
[https://www.uniprot.org/uniprot/HIS4_STRCO HIS4_STRCO] Catalyzes the isomerization of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR in the biosynthesis pathway for histidine and the isomerization of the aminoaldose PRA to the aminoketose CdRP in the biosynthsis pathway for tryptophan.[HAMAP-Rule:MF_01014]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Strco]]
[[Category: Large Structures]]
[[Category: Barona-Gomez, F]]
[[Category: Barona-Gomez F]]
[[Category: Chang, C]]
[[Category: Chang C]]
[[Category: Endres, M]]
[[Category: Endres M]]
[[Category: Joachimiak, A]]
[[Category: Joachimiak A]]
[[Category: Structural genomic]]
[[Category: Verduzco-Castro EA]]
[[Category: Verduzco-Castro, E A]]
[[Category: Histidine biosynthesis]]
[[Category: Isomerase]]
[[Category: Mcsg]]
[[Category: Psi-biology]]
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