8a5b: Difference between revisions
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==Crystal structure of human cathepsin L in complex with covalently bound MG-101== | |||
<StructureSection load='8a5b' size='340' side='right'caption='[[8a5b]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8a5b]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A5B FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2DO:(2S)-2-AMINOHEXANE-1,1-DIOL'>2DO</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a5b OCA], [https://pdbe.org/8a5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a5b RCSB], [https://www.ebi.ac.uk/pdbsum/8a5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a5b ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Chapman HN]] | |||
[[Category: Ewert W]] | |||
[[Category: Falke S]] | |||
[[Category: Guenther S]] | |||
[[Category: Hinrichs W]] | |||
[[Category: Karnicar K]] | |||
[[Category: Lieske J]] | |||
[[Category: Lindic N]] | |||
[[Category: Loboda J]] | |||
[[Category: Meents A]] | |||
[[Category: Reinke PYA]] | |||
[[Category: Sekirnik A]] | |||
[[Category: Turk D]] | |||
[[Category: Usenik A]] | |||
Latest revision as of 05:39, 5 July 2023
Crystal structure of human cathepsin L in complex with covalently bound MG-101
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