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==NMR solution structure of a disulfide analogue of the cyclic sunflower trypsin inhibitor SFTI-1==
==NMR solution structure of a disulfide analogue of the cyclic sunflower trypsin inhibitor SFTI-1==
<StructureSection load='1t9e' size='340' side='right'caption='[[1t9e]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1t9e' size='340' side='right'caption='[[1t9e]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1t9e]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T9E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T9E FirstGlance]. <br>
<table><tr><td colspan='2'>[[1t9e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helianthus_annuus Helianthus annuus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T9E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T9E FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1sfi|1sfi]], [[1jbl|1jbl]], [[1jbn|1jbn]], [[1o8y|1o8y]], [[1o8z|1o8z]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t9e OCA], [https://pdbe.org/1t9e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t9e RCSB], [https://www.ebi.ac.uk/pdbsum/1t9e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t9e ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t9e OCA], [https://pdbe.org/1t9e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t9e RCSB], [https://www.ebi.ac.uk/pdbsum/1t9e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t9e ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/SFTI1_HELAN SFTI1_HELAN]] Inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. Does not inhibit factor Xa.<ref>PMID:10390350</ref>
[https://www.uniprot.org/uniprot/SFTI1_HELAN SFTI1_HELAN] Inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. Does not inhibit factor Xa.<ref>PMID:10390350</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Helianthus annuus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Clark, R J]]
[[Category: Clark RJ]]
[[Category: Craik, D J]]
[[Category: Craik DJ]]
[[Category: Korsinczky, M L.J]]
[[Category: Korsinczky MLJ]]
[[Category: Disulfide mutant]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Sunflower trypsin inhibitor]]
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