5en1: Difference between revisions
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==Crystal structure of hnRNPA2B1 in complex with RNA== | ==Crystal structure of hnRNPA2B1 in complex with RNA== | ||
<StructureSection load='5en1' size='340' side='right' caption='[[5en1]], [[Resolution|resolution]] 2.58Å' scene=''> | <StructureSection load='5en1' size='340' side='right'caption='[[5en1]], [[Resolution|resolution]] 2.58Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5en1]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5en1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EN1 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.58Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5en1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5en1 OCA], [https://pdbe.org/5en1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5en1 RCSB], [https://www.ebi.ac.uk/pdbsum/5en1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5en1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN] Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN] Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus. | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Ma JB]] | ||
[[Category: | [[Category: Su SC]] | ||
[[Category: | [[Category: Wu BX]] | ||
Latest revision as of 08:07, 12 July 2023
Crystal structure of hnRNPA2B1 in complex with RNA
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