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<StructureSection load='5epn' size='340' side='right'caption='[[5epn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='5epn' size='340' side='right'caption='[[5epn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5epn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/9hepc 9hepc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EPN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5EPN FirstGlance]. <br>
<table><tr><td colspan='2'>[[5epn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EPN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5R2:2-METHYL-2-PROPANYL+{(2R,6S,12Z,13AS,14AR,16AS)-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-2-[(3-ETHYL-7-METHOXY-2-QUINOXALINYL)OXY]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOP+ROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-6-YL}CARBAMATE'>5R2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5epy|5epy]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5R2:2-METHYL-2-PROPANYL+{(2R,6S,12Z,13AS,14AR,16AS)-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-2-[(3-ETHYL-7-METHOXY-2-QUINOXALINYL)OXY]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOP+ROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-6-YL}CARBAMATE'>5R2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5epn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5epn OCA], [http://pdbe.org/5epn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5epn RCSB], [http://www.ebi.ac.uk/pdbsum/5epn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5epn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5epn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5epn OCA], [https://pdbe.org/5epn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5epn RCSB], [https://www.ebi.ac.uk/pdbsum/5epn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5epn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/C1KIK8_9HEPC C1KIK8_9HEPC]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5epn" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5epn" style="background-color:#fffaf0;"></div>
==See Also==
*[[Virus protease 3D structures|Virus protease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hepacivirus C]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ali, A]]
[[Category: Ali A]]
[[Category: Aydin, C]]
[[Category: Aydin C]]
[[Category: Prachanronarong, K L]]
[[Category: Prachanronarong KL]]
[[Category: Schiffer, C A]]
[[Category: Schiffer CA]]
[[Category: Soumana, D I]]
[[Category: Soumana DI]]
[[Category: Yilmaz, N K]]
[[Category: Yilmaz NK]]
[[Category: Grazoprevir]]
[[Category: Hcv protease inhibitor resistance]]
[[Category: Hydrolase]]
[[Category: Macrocyclization]]
[[Category: Mk-5172 analogue]]