5eqp: Difference between revisions

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<StructureSection load='5eqp' size='340' side='right'caption='[[5eqp]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='5eqp' size='340' side='right'caption='[[5eqp]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5eqp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5EQP FirstGlance]. <br>
<table><tr><td colspan='2'>[[5eqp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EQP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5R9:6-[(4-METHYL-1,4-DIAZEPAN-1-YL)METHYL]QUINOLINE'>5R9</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5eqe|5eqe]], [[5eqy|5eqy]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5R9:6-[(4-METHYL-1,4-DIAZEPAN-1-YL)METHYL]QUINOLINE'>5R9</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHKA, CHK, CKI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eqp OCA], [https://pdbe.org/5eqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eqp RCSB], [https://www.ebi.ac.uk/pdbsum/5eqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eqp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5eqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eqp OCA], [http://pdbe.org/5eqp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eqp RCSB], [http://www.ebi.ac.uk/pdbsum/5eqp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eqp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CHKA_HUMAN CHKA_HUMAN]] Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.<ref>PMID:19915674</ref>
[https://www.uniprot.org/uniprot/CHKA_HUMAN CHKA_HUMAN] Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.<ref>PMID:19915674</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Dalgarno, D C]]
[[Category: Dalgarno DC]]
[[Category: Zhou, T]]
[[Category: Zhou T]]
[[Category: Zhu, X]]
[[Category: Zhu X]]
[[Category: Complex]]
[[Category: Drug target]]
[[Category: Inhibitor]]
[[Category: Kinase]]
[[Category: Transferase-transferase inhibitor complex]]
Retrieved from "https://proteopedia.org/5eqp"