5f6c: Difference between revisions

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==The structure of E. coli RNase E catalytically inactive mutant with RNA bound==
==The structure of E. coli RNase E catalytically inactive mutant with RNA bound==
<StructureSection load='5f6c' size='340' side='right' caption='[[5f6c]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='5f6c' size='340' side='right'caption='[[5f6c]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5f6c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F6C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F6C FirstGlance]. <br>
<table><tr><td colspan='2'>[[5f6c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F6C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F6C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.002&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rne, ams, hmp1, b1084, JW1071 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_E Ribonuclease E], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.12 3.1.26.12] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f6c OCA], [https://pdbe.org/5f6c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f6c RCSB], [https://www.ebi.ac.uk/pdbsum/5f6c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f6c ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f6c OCA], [http://pdbe.org/5f6c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f6c RCSB], [http://www.ebi.ac.uk/pdbsum/5f6c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5f6c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RNE_ECOLI RNE_ECOLI]] Matures 5S rRNA from its precursors from all the rRNA genes. It also cleaves RNA I, a molecule that controls the replication of colE1 plasmid DNA. It is the major endoribonuclease participating in mRNA turnover in E.coli. It initiates the decay of RNAs by cutting them internally near their 5'-end. It is able to remove poly(A) tails by an endonucleolytic process.  
[https://www.uniprot.org/uniprot/RNE_ECOLI RNE_ECOLI] Matures 5S rRNA from its precursors from all the rRNA genes. It also cleaves RNA I, a molecule that controls the replication of colE1 plasmid DNA. It is the major endoribonuclease participating in mRNA turnover in E.coli. It initiates the decay of RNAs by cutting them internally near their 5'-end. It is able to remove poly(A) tails by an endonucleolytic process.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Ribonuclease|Ribonuclease]]
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli]]
[[Category: Ribonuclease E]]
[[Category: Escherichia coli K-12]]
[[Category: Bandyra, K J]]
[[Category: Large Structures]]
[[Category: Luisi, B F]]
[[Category: Bandyra KJ]]
[[Category: Hydrolase]]
[[Category: Luisi BF]]
[[Category: Hydrolytic mechanism]]
[[Category: Regulatory rna]]
[[Category: Ribonuclease]]