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==Fumarate hydratase of Mycobacterium tuberculosis in complex with formate==
==Fumarate hydratase of Mycobacterium tuberculosis in complex with formate==
<StructureSection load='5f92' size='340' side='right' caption='[[5f92]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
<StructureSection load='5f92' size='340' side='right'caption='[[5f92]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5f92]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycto Mycto]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F92 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5f92]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_CDC1551 Mycobacterium tuberculosis CDC1551]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F92 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.859&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f91|5f91]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fumC, fum, MT1130 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83331 MYCTO])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f92 OCA], [https://pdbe.org/5f92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f92 RCSB], [https://www.ebi.ac.uk/pdbsum/5f92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f92 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fumarate_hydratase Fumarate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.2 4.2.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f92 OCA], [http://pdbe.org/5f92 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f92 RCSB], [http://www.ebi.ac.uk/pdbsum/5f92 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5f92 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FUMC_MYCTO FUMC_MYCTO]] Catalyzes the reversible addition of water to fumarate to give L-malate.  
[https://www.uniprot.org/uniprot/FUMC_MYCTU FUMC_MYCTU] Catalyzes the reversible addition of water to fumarate to give L-malate.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5f92" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5f92" style="background-color:#fffaf0;"></div>
==See Also==
*[[Fumarase|Fumarase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fumarate hydratase]]
[[Category: Large Structures]]
[[Category: Mycto]]
[[Category: Mycobacterium tuberculosis CDC1551]]
[[Category: Abell, C]]
[[Category: Abell C]]
[[Category: Barry, C E]]
[[Category: Barry CE]]
[[Category: Boshoff, H I]]
[[Category: Boshoff HI]]
[[Category: Fischer, G]]
[[Category: Fischer G]]
[[Category: Hyvonen, M]]
[[Category: Hyvonen M]]
[[Category: Kasbekar, M]]
[[Category: Kasbekar M]]
[[Category: Mott, B T]]
[[Category: Mott BT]]
[[Category: Thomas, C J]]
[[Category: Thomas CJ]]
[[Category: Yasgar, A]]
[[Category: Yasgar A]]
[[Category: Hydratase]]
[[Category: Lyase]]
[[Category: Metabolism]]
[[Category: Tuberculosis]]
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