2dde: Difference between revisions
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==Structure of cinnamycin complexed with lysophosphatidylethanolamine== | ==Structure of cinnamycin complexed with lysophosphatidylethanolamine== | ||
<StructureSection load='2dde' size='340' side='right'caption='[[2dde | <StructureSection load='2dde' size='340' side='right'caption='[[2dde]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2dde]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DDE FirstGlance]. <br> | <table><tr><td colspan='2'>[[2dde]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseoverticillatus Streptomyces griseoverticillatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DDE FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=LSP:(7S)-4,7-DIHYDROXY-10-OXO-3,5,9-TRIOXA-4-PHOSPHAUNDECAN-1-AMINIUM+4-OXIDE'>LSP</scene>, <scene name='pdbligand=PRD_000195:Cinnamycin'>PRD_000195</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [https://pdbe.org/2dde PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [https://www.ebi.ac.uk/pdbsum/2dde PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dde ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dde OCA], [https://pdbe.org/2dde PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dde RCSB], [https://www.ebi.ac.uk/pdbsum/2dde PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dde ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CINA_STRGV CINA_STRGV] Can act as inhibitor of the enzyme phospholipase A2, and of the angiotensin-converting enzyme. Shows inhibitory activities against herpes simplex virus and immunopotentiating activities. Its antimicrobial activities are not very pronounced. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Streptomyces griseoverticillatus]] | [[Category: Streptomyces griseoverticillatus]] | ||
[[Category: Endo | [[Category: Endo S]] | ||
[[Category: Hosoda | [[Category: Hosoda K]] | ||
[[Category: Kohno | [[Category: Kohno T]] | ||
[[Category: Maeda | [[Category: Maeda T]] | ||
[[Category: Ohya | [[Category: Ohya M]] | ||
[[Category: Wakamatsu | [[Category: Wakamatsu K]] | ||