2jnr: Difference between revisions
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==Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide== | ==Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide== | ||
<StructureSection load='2jnr' size='340' side='right'caption='[[2jnr | <StructureSection load='2jnr' size='340' side='right'caption='[[2jnr]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jnr]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JNR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JNR FirstGlance]. <br> | <table><tr><td colspan='2'>[[2jnr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JNR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JNR FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jnr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jnr OCA], [https://pdbe.org/2jnr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jnr RCSB], [https://www.ebi.ac.uk/pdbsum/2jnr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jnr ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jnr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jnr OCA], [https://pdbe.org/2jnr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jnr RCSB], [https://www.ebi.ac.uk/pdbsum/2jnr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jnr ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/Q72502_9HIV1 Q72502_9HIV1] The envelope glyprotein gp160 precursor down-modulates cell surface CD4 antigen by interacting with it in the endoplasmic reticulum and blocking its transport to the cell surface.[RuleBase:RU004292] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Adermann | [[Category: Synthetic construct]] | ||
[[Category: Biet | [[Category: Adermann K]] | ||
[[Category: Chaipan | [[Category: Biet T]] | ||
[[Category: Forssmann | [[Category: Chaipan C]] | ||
[[Category: Jiang | [[Category: Forssmann W]] | ||
[[Category: Jing | [[Category: Jiang S]] | ||
[[Category: Kirchhoff | [[Category: Jing W]] | ||
[[Category: Lu | [[Category: Kirchhoff F]] | ||
[[Category: Meyer | [[Category: Lu H]] | ||
[[Category: Munch | [[Category: Meyer B]] | ||
[[Category: Peters | [[Category: Munch J]] | ||
[[Category: Pohlmann | [[Category: Peters T]] | ||
[[Category: Schulz | [[Category: Pohlmann S]] | ||
[[Category: Standker | [[Category: Schulz A]] | ||
[[Category: Wilhelm | [[Category: Standker L]] | ||
[[Category: Wilhelm D]] | |||
