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==PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES==
==PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES==
<StructureSection load='2pta' size='340' side='right'caption='[[2pta]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2pta' size='340' side='right'caption='[[2pta]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Emperor_scorpion Emperor scorpion]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PTA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pandinus_imperator Pandinus imperator]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PTA FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [https://pdbe.org/2pta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [https://www.ebi.ac.uk/pdbsum/2pta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pta ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [https://pdbe.org/2pta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [https://www.ebi.ac.uk/pdbsum/2pta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pta ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/KAX71_PANIM KAX71_PANIM]] Potent inhibitor of the A-type voltage-gated potassium channels. Most potent inhibitor of Kv1.2/KCNA2 channels. Reversibly block the Shaker B potassium-channels (Kv1.1 sub-family).<ref>PMID:8660410</ref>
[https://www.uniprot.org/uniprot/KAX71_PANIM KAX71_PANIM] Potent inhibitor of the A-type voltage-gated potassium channels. Most potent inhibitor of Kv1.2/KCNA2 channels. Reversibly block the Shaker B potassium-channels (Kv1.1 sub-family).<ref>PMID:8660410</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Emperor scorpion]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Blaustein, M P]]
[[Category: Pandinus imperator]]
[[Category: Collins, J H]]
[[Category: Blaustein MP]]
[[Category: Rogowski, R S]]
[[Category: Collins JH]]
[[Category: Tenenholz, T C]]
[[Category: Rogowski RS]]
[[Category: Weber, D J]]
[[Category: Tenenholz TC]]
[[Category: Alpha-k toxin family]]
[[Category: Weber DJ]]
[[Category: Neurotoxin]]
[[Category: Nmr solution structure]]
[[Category: Potassium channel blocker]]
[[Category: Scorpion toxin]]
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