5ftg: Difference between revisions

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<StructureSection load='5ftg' size='340' side='right'caption='[[5ftg]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='5ftg' size='340' side='right'caption='[[5ftg]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ftg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FTG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FTG FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ftg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FTG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FTG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NBR:1-[[4-[2-[4-[[4-(DIMETHYLAMINO)PYRIDIN-1-YL]METHYL]PHENOXY]ETHOXY]PHENYL]METHYL]-N,N-DIMETHYL-PYRIDIN-4-AMINE'>NBR</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ftg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ftg OCA], [http://pdbe.org/5ftg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ftg RCSB], [http://www.ebi.ac.uk/pdbsum/5ftg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ftg ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NBR:1-[[4-[2-[4-[[4-(DIMETHYLAMINO)PYRIDIN-1-YL]METHYL]PHENOXY]ETHOXY]PHENYL]METHYL]-N,N-DIMETHYL-PYRIDIN-4-AMINE'>NBR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ftg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ftg OCA], [https://pdbe.org/5ftg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ftg RCSB], [https://www.ebi.ac.uk/pdbsum/5ftg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ftg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CHKA_HUMAN CHKA_HUMAN]] Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.<ref>PMID:19915674</ref>
[https://www.uniprot.org/uniprot/CHKA_HUMAN CHKA_HUMAN] Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.<ref>PMID:19915674</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Baglioni, E]]
[[Category: Baglioni E]]
[[Category: Basso, G]]
[[Category: Basso G]]
[[Category: Bortolozzi, R]]
[[Category: Bortolozzi R]]
[[Category: Carrasco-Jimenez, M P]]
[[Category: Carrasco-Jimenez MP]]
[[Category: Entrena, A]]
[[Category: Entrena A]]
[[Category: Gallo, M A]]
[[Category: Gallo MA]]
[[Category: Hurtado-Guerrero, R]]
[[Category: Hurtado-Guerrero R]]
[[Category: Lopez-Cara, L C]]
[[Category: Lopez-Cara LC]]
[[Category: Marco, C]]
[[Category: Marco C]]
[[Category: Mariotto, E]]
[[Category: Mariotto E]]
[[Category: Rios-Marco, P]]
[[Category: Rios-Marco P]]
[[Category: Schiaffino-Ortega, S]]
[[Category: Schiaffino-Ortega S]]
[[Category: Serran-Aguilera, L]]
[[Category: Serran-Aguilera L]]
[[Category: Viola, G]]
[[Category: Viola G]]
[[Category: Biscationic inhibitor]]
[[Category: Docking study]]
[[Category: Transferase]]
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