5fuq: Difference between revisions

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<StructureSection load='5fuq' size='340' side='right'caption='[[5fuq]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
<StructureSection load='5fuq' size='340' side='right'caption='[[5fuq]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fuq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5FUQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fuq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FUQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DTC:BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE]'>DTC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(P)H_dehydrogenase_(quinone) NAD(P)H dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.2 1.6.5.2] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DTC:BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE]'>DTC</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5fuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fuq OCA], [http://pdbe.org/5fuq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fuq RCSB], [http://www.ebi.ac.uk/pdbsum/5fuq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fuq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fuq OCA], [https://pdbe.org/5fuq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fuq RCSB], [https://www.ebi.ac.uk/pdbsum/5fuq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fuq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NQO1_HUMAN NQO1_HUMAN]] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.  
[https://www.uniprot.org/uniprot/NQO1_HUMAN NQO1_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.


==See Also==
==See Also==
*[[NADPH dehydrogenase|NADPH dehydrogenase]]
*[[NADPH dehydrogenase|NADPH dehydrogenase]]
*[[Quinone reductase|Quinone reductase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Gavira, J A]]
[[Category: Gavira JA]]
[[Category: Medina-Carmona, E]]
[[Category: Medina-Carmona E]]
[[Category: Pey, A L]]
[[Category: Pey AL]]
[[Category: Dicoumarol]]
[[Category: Fad]]
[[Category: Nadph-quinone oxidoreductase 1]]
[[Category: Nqo1]]
[[Category: Oxidoreductase]]
Retrieved from "https://proteopedia.org/5fuq"