7msf: Difference between revisions

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==MS2 PROTEIN CAPSID/RNA COMPLEX==
==MS2 PROTEIN CAPSID/RNA COMPLEX==
<StructureSection load='7msf' size='340' side='right' caption='[[7msf]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='7msf' size='340' side='right'caption='[[7msf]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7msf]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=7MSF FirstGlance]. <br>
<table><tr><td colspan='2'>[[7msf]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MSF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MSF FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">COAT PROTEIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12022 Bacteriophage MS2])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=7msf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7msf OCA], [http://pdbe.org/7msf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7msf RCSB], [http://www.ebi.ac.uk/pdbsum/7msf PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7msf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7msf OCA], [https://pdbe.org/7msf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7msf RCSB], [https://www.ebi.ac.uk/pdbsum/7msf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7msf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.  
[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/7msf_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/7msf_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacteriophage ms2]]
[[Category: Escherichia phage MS2]]
[[Category: Adams, C J]]
[[Category: Large Structures]]
[[Category: Convery, M A]]
[[Category: Adams CJ]]
[[Category: Ellington, A D]]
[[Category: Convery MA]]
[[Category: Hirao, I]]
[[Category: Ellington AD]]
[[Category: Peabody, D S]]
[[Category: Hirao I]]
[[Category: Phillips, S E.V]]
[[Category: Peabody DS]]
[[Category: Rowsell, S]]
[[Category: Phillips SEV]]
[[Category: Stockley, P G]]
[[Category: Rowsell S]]
[[Category: Stonehouse, N J]]
[[Category: Stockley PG]]
[[Category: Ccapsid protein ms2-rna aptamer complex]]
[[Category: Stonehouse NJ]]
[[Category: Icosahedral virus]]
[[Category: Rna stem loop]]
[[Category: Rna-protein complex]]
[[Category: Virus-rna complex]]
Retrieved from "https://proteopedia.org/7msf"