1ork: Difference between revisions

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<StructureSection load='1ork' size='340' side='right'caption='[[1ork]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='1ork' size='340' side='right'caption='[[1ork]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ork]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ORK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ORK FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ork]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ORK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ORK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATC:9-(N,N-DIMETHYLGLYCYLAMIDO)-6-DEOXY-6-DEMETHYL-TETRACYCLINE'>ATC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATC:9-(N,N-DIMETHYLGLYCYLAMIDO)-6-DEOXY-6-DEMETHYL-TETRACYCLINE'>ATC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ork FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ork OCA], [https://pdbe.org/1ork PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ork RCSB], [https://www.ebi.ac.uk/pdbsum/1ork PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ork ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ork FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ork OCA], [https://pdbe.org/1ork PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ork RCSB], [https://www.ebi.ac.uk/pdbsum/1ork PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ork ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/TETR4_ECOLX TETR4_ECOLX]] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.  
[https://www.uniprot.org/uniprot/TETR4_ECOLX TETR4_ECOLX] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ellestad, G A]]
[[Category: Ellestad GA]]
[[Category: Hillen, W]]
[[Category: Hillen W]]
[[Category: Hinrichs, W]]
[[Category: Hinrichs W]]
[[Category: Orth, P]]
[[Category: Orth P]]
[[Category: Saenger, W]]
[[Category: Saenger W]]
[[Category: Schnappinger, D]]
[[Category: Schnappinger D]]
[[Category: Sum, P E]]
[[Category: Sum P-E]]
[[Category: Transcription regulation]]
Retrieved from "https://proteopedia.org/1ork"